Migrinol (Magnesium + Riboflavin + CoQ10)

Migrinol is a nutraceutical supplement taken to help prevent recurrent migraine attacks. It has received a Level 2 recommendation from the American Headache Society, Canadian Headache Society, and European Headache Society as a supplement that helps in migraine prevention.

It contains a high amount of magnesium, which helps regulate the overactivity of neurons that trigger migraines.

It also helps inhibit the synthesis and release of chemicals that cause pain and inflammation during migraine attacks.

Riboflavin and Coenzyme Q10 (CoQ10) help provide energy to cells and maintain proper mitochondrial function, which helps control inflammation and pain during migraine attacks.

In addition to being a migraine-preventive supplement, it also provides the following benefits:
Magnesium

Improves insulin and glucose metabolism

Strengthens smooth muscles for better blood flow

Improves lipid profile

Riboflavin

Provides protection against cardiac tissue damage

Coenzyme Q10

Improves cellular energy transformation

Helps prevent the formation of LDL (bad cholesterol)

Provides protection against blood thickening (clot formation)

HOW TO USE MIGRINOL

The recommended dosage is one to two capsules per day.

The best time to take it is in the morning, after meals, or as advised by your doctor.

ADDITIONAL INFORMATION

Studies have revealed decreased levels of the micronutrients riboflavin, magnesium, and coenzyme Q10 in the plasma and brain of migraine patients. Mitochondrial dysfunction plays an important role in migraine. CoQ10 plays a crucial role in energy production within the mitochondria.

Treatment of migraine with nutritional supplements may be beneficial for patients with recurrent migraines who cannot tolerate chemical drugs due to side effects or contraindications related to coexisting diseases.

Magnesium

Magnesium is the physiological antagonist at the NMDA receptor channel, which is involved in regulating neuronal excitability. Magnesium is required for various physiological processes that influence the pathophysiology of migraine, such as vasoconstriction, platelet inhibition, and serotonin secretion. Some studies have shown low brain magnesium levels during migraine attacks. Because magnesium deficiency is thought to be related to migraines, it is considered an important element in migraine aura and a natural remedy for migraines.

Riboflavin (Vitamin B2)

Riboflavin is a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), both of which are responsible for electron transport in the mitochondrial membrane.

Coenzyme Q10

Coenzyme Q10 is a vitamin-like compound that can be synthesized by the body from phenylalanine and tyrosine. It is required for all cellular processes that need energy. Coenzyme Q10 acts as an electron carrier, transferring electrons from Complex I / Complex II to cytochrome C.